Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas

Both somatic hypermutation (SHM) and class switch recombination (CSR) are initiated by activation-induced cytidine deaminase (AID). Dysregulation of these processes has been linked to B cell lymphomagenesis. Here we performed an in-depth analysis of diffuse large B cell lymphoma (DLBCL) and follicul...

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Detalles Bibliográficos
Autores principales: Ye, Xiaofei, Ren, Weicheng, Liu, Dongbing, Li, Xiaobo, Li, Wei, Wang, Xianhuo, Meng, Fei-Long, Yeap, Leng-Siew, Hou, Yong, Zhu, Shida, Casellas, Rafael, Zhang, Huilai, Wu, Kui, Pan-Hammarström, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Technical Advances and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608067/
https://www.ncbi.nlm.nih.gov/pubmed/33136155
http://dx.doi.org/10.1084/jem.20200573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608067/
https://www.ncbi.nlm.nih.gov/pubmed/33136155
http://dx.doi.org/10.1084/jem.20200573

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