Cargando…

Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?

Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculos...

Descripción completa

Detalles Bibliográficos
Autores principales: Santos, Ana Carolina Etrusco Zaroni, Sztajnbok, Jaques, Duarte-Neto, Amaro Nunes, Sousa, Amanda Freire Tamburini, Lopes, Alessandra Geisler Daud, Barrientos, Anna Carlota Mott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608070/
https://www.ncbi.nlm.nih.gov/pubmed/33146307
http://dx.doi.org/10.1590/S1678-9946202062078
Descripción
Sumario:Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs.