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Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use?
Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608070/ https://www.ncbi.nlm.nih.gov/pubmed/33146307 http://dx.doi.org/10.1590/S1678-9946202062078 |
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author | Santos, Ana Carolina Etrusco Zaroni Sztajnbok, Jaques Duarte-Neto, Amaro Nunes Sousa, Amanda Freire Tamburini Lopes, Alessandra Geisler Daud Barrientos, Anna Carlota Mott |
author_facet | Santos, Ana Carolina Etrusco Zaroni Sztajnbok, Jaques Duarte-Neto, Amaro Nunes Sousa, Amanda Freire Tamburini Lopes, Alessandra Geisler Daud Barrientos, Anna Carlota Mott |
author_sort | Santos, Ana Carolina Etrusco Zaroni |
collection | PubMed |
description | Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs. |
format | Online Article Text |
id | pubmed-7608070 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Instituto de Medicina Tropical |
record_format | MEDLINE/PubMed |
spelling | pubmed-76080702020-11-13 Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? Santos, Ana Carolina Etrusco Zaroni Sztajnbok, Jaques Duarte-Neto, Amaro Nunes Sousa, Amanda Freire Tamburini Lopes, Alessandra Geisler Daud Barrientos, Anna Carlota Mott Rev Inst Med Trop Sao Paulo Case Report Disseminated tuberculosis is a severe disease with high-mortality that requires early diagnosis and treatment. Intestinal tuberculosis accounts for only 2% of tuberculosis cases worldwide and is extremely rare in children. We report a case of a 4-year-old girl admitted due to disseminated tuberculosis with extensive intestinal involvement characterized by massive intestinal bleeding and hemorrhagic shock. The severity of the intestinal involvement precluded the exclusive use of oral anti-tuberculosis drugs and the patient was successfully treated with a combination of injectable and oral anti-tuberculosis agents. We discuss the importance of a regimen with injectable drugs for treating severe forms of tuberculosis in which the intestinal involvement impaired the use of oral drugs. Instituto de Medicina Tropical 2020-10-30 /pmc/articles/PMC7608070/ /pubmed/33146307 http://dx.doi.org/10.1590/S1678-9946202062078 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Santos, Ana Carolina Etrusco Zaroni Sztajnbok, Jaques Duarte-Neto, Amaro Nunes Sousa, Amanda Freire Tamburini Lopes, Alessandra Geisler Daud Barrientos, Anna Carlota Mott Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title | Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title_full | Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title_fullStr | Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title_full_unstemmed | Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title_short | Severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
title_sort | severe gastrintestinal bleeding as an unusual presentation of pediatric tuberculosis: a situation for injectable antituberculous drugs use? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608070/ https://www.ncbi.nlm.nih.gov/pubmed/33146307 http://dx.doi.org/10.1590/S1678-9946202062078 |
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