Cargando…

Gastrodin protects H9c2 cardiomyocytes against oxidative injury by ameliorating imbalanced mitochondrial dynamics and mitochondrial dysfunction

Gastrodin (GAS) is the main bioactive component of Tianma, a traditional Chinese medicine widely used to treat neurological disorders as well as cardio- and cerebrovascular diseases. In the present study, the protective effects of GAS on H9c2 cells against ischemia–reperfusion (IR)-like injury were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Qiao-qiao, Wan, Yu-wei, Yang, Wei-min, Tian, Meng-hua, Wang, Yu-chuan, He, Hai-yan, Zhang, Wei-dong, Liu, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608121/ https://www.ncbi.nlm.nih.gov/pubmed/32203078 http://dx.doi.org/10.1038/s41401-020-0382-x

Ejemplares similares

Gastrodin and Gastrodigenin Improve Energy Metabolism Disorders and Mitochondrial Dysfunction to Antagonize Vascular Dementia
por: Wu, Sha, et al.
Publicado: (2023)

Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3η
por: Zhu, Meifang, et al.
Publicado: (2018)

Gastrodin ameliorates cognitive dysfunction in diabetes by inhibiting PAK2 phosphorylation
por: Mu, Zhi-Hao, et al.
Publicado: (2023)

Levocarnitine Protects H9c2 Rat Cardiomyocytes from H(2)O(2)-induced Mitochondrial Dysfunction and Apoptosis
por: Mao, Cui-Ying, et al.
Publicado: (2014)

OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases
por: Wu, Wei, et al.
Publicado: (2019)

HO-1 Protects against Hypoxia/Reoxygenation-Induced Mitochondrial Dysfunction in H9c2 Cardiomyocytes
por: Chen, Dongling, et al.
Publicado: (2016)

Redox mechanisms of cardiomyocyte mitochondrial protection
por: Bartz, Raquel R., et al.
Publicado: (2015)

Bioactive Compounds from Germinated Brown Rice Protect Cardiomyocytes Against Simulated Ischemic/Reperfusion Injury by Ameliorating Mitochondrial Dysfunction
por: Demeekul, Kanokwan, et al.
Publicado: (2021)

Macrophage-Derived Exosomes in TLR9(−/−) Mice Ameliorate Sepsis-Induced Mitochondrial Oxidative Stress and Apoptosis in Cardiomyocytes
por: Li, Xiang, et al.
Publicado: (2022)

Re‐equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction
por: Sun, Chongkui, et al.
Publicado: (2020)

CXCR4 attenuates cardiomyocytes mitochondrial dysfunction to resist ischaemia-reperfusion injury
por: Cai, Wen-Feng, et al.
Publicado: (2015)

Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
por: Ye, Tianyuan, et al.
Publicado: (2018)

A novel mutation in human EMD gene and mitochondrial dysfunction in emerin knockdown cardiomyocytes
por: Du, Zunhui, et al.
Publicado: (2022)

Mitochondrial-Derived Vesicles Protect Cardiomyocytes Against Hypoxic Damage
por: Li, Binghu, et al.
Publicado: (2020)

Traditional Chinese Medicine Ginseng Dingzhi Decoction Ameliorates Myocardial Fibrosis and High Glucose-Induced Cardiomyocyte Injury by Regulating Intestinal Flora and Mitochondrial Dysfunction
por: Wang, Junyan, et al.
Publicado: (2022)

Lycopene Protects against Hypoxia/Reoxygenation-Induced Apoptosis by Preventing Mitochondrial Dysfunction in Primary Neonatal Mouse Cardiomyocytes
por: Yue, Rongchuan, et al.
Publicado: (2012)

Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways
por: Wang, Yu, et al.
Publicado: (2016)

FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction
por: Croon, Marijana, et al.
Publicado: (2022)

Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p
por: Song, Jin-Jin, et al.
Publicado: (2022)

The Complex Interplay between Imbalanced Mitochondrial Dynamics and Metabolic Disorders in Type 2 Diabetes
por: Van Huynh, Tin, et al.
Publicado: (2023)

C-Phycocyanin Ameliorates Mitochondrial Fission and Fusion Dynamics in Ischemic Cardiomyocyte Damage
por: Gao, Jinchao, et al.
Publicado: (2019)

Retracted: Macrophage-Derived Exosomes in TLR9-/- Mice Ameliorate Sepsis-Induced Mitochondrial Oxidative Stress and Apoptosis in Cardiomyocytes
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism
por: Bai, Yu, et al.
Publicado: (2021)

Tetramethylpyrazine Ameliorates High Glucose-Induced Endothelial Dysfunction by Increasing Mitochondrial Biogenesis
por: Xu, Qiong, et al.
Publicado: (2014)

Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation
por: Li, Shishi, et al.
Publicado: (2018)

Mitochondrial Dysfunction Underlies Cardiomyocyte Remodeling in Experimental and Clinical Atrial Fibrillation
por: Wiersma, Marit, et al.
Publicado: (2019)

Gastrodin and Vascular Dementia: Advances and Current Perspectives
por: Deng, Chujun, et al.
Publicado: (2022)

Matrine Protects Cardiomyocytes Against Hyperglycemic Stress by Promoting Mitofusin 2-Induced Mitochondrial Fusion
por: Xiao, Tong, et al.
Publicado: (2021)

Clinical therapeutic effects of gastrodin in combination with betahistine on vertigo: A protocol for systematic review and meta-analysis
por: Qiao, Yu-Lin, et al.
Publicado: (2021)

Gastrodin Reduces Blood Pressure by Intervening with RAAS and PPARγ in SHRs
por: Liu, Wei, et al.
Publicado: (2015)

Exenatide Reduces Tumor Necrosis Factor-α-induced Apoptosis in Cardiomyocytes by Alleviating Mitochondrial Dysfunction
por: Cao, Yuan-Yuan, et al.
Publicado: (2015)

Protective effect of gastrodin on myocardial ischemia-reperfusion injury and the expression of Bax and Bcl-2
por: Han, Xiao, et al.
Publicado: (2019)

Testosterone ameliorates age-related brain mitochondrial dysfunction
por: Yan, Wensheng, et al.
Publicado: (2021)

Mitochondrial Biogenesis, Mitochondrial Dynamics, and Mitophagy in the Maturation of Cardiomyocytes
por: Ding, Qianqian, et al.
Publicado: (2021)

Capsaicin Protects Cardiomyocytes against Anoxia/Reoxygenation Injury via Preventing Mitochondrial Dysfunction Mediated by SIRT1
por: He, Huan, et al.
Publicado: (2017)

Metformin protects high glucose-cultured cardiomyocytes from oxidative stress by promoting NDUFA13 expression and mitochondrial biogenesis via the AMPK signaling pathway
por: Liu, Xiang-Dong, et al.
Publicado: (2020)

Gastrodin protects against chronic inflammatory pain by inhibiting spinal synaptic potentiation
por: Xiao, Mei-Mei, et al.
Publicado: (2016)

Gastrodin Ameliorates Motor Learning Deficits Through Preserving Cerebellar Long-Term Depression Pathways in Diabetic Rats
por: Deng, Cheng-Kun, et al.
Publicado: (2019)

Mitochondrial Dynamics in Adult Cardiomyocytes and Heart Diseases
por: Li, Anqi, et al.
Publicado: (2020)

COX6B1 relieves hypoxia/reoxygenation injury of neonatal rat cardiomyocytes by regulating mitochondrial function
por: Zhang, Wei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l44gilvpoaqvnkodhf474q3cfj