ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells

Programmed DNA recombination in mammalian cells occurs predominantly in a directional manner. While random DNA breaks are typically repaired both by deletion and by inversion at approximately equal proportions, V(D)J and class switch recombination (CSR) of immunoglobulin heavy chain gene overwhelmin...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojing, Liu, Tingting, Shang, Yafang, Dai, Pengfei, Zhang, Wubing, Lee, Brian J., Huang, Min, Yang, Dingpeng, Wu, Qiu, Liu, Liu Daisy, Zheng, Xiaoqi, Zhou, Bo O., Dong, Junchao, Yeap, Leng-Siew, Hu, Jiazhi, Xiao, Tengfei, Zha, Shan, Casellas, Rafael, Liu, X. Shirley, Meng, Fei-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608219/
https://www.ncbi.nlm.nih.gov/pubmed/32355287
http://dx.doi.org/10.1038/s41422-020-0328-3

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