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Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety
Major depressive disorder is associated with lowered mood, anxiety, anhedonia, sleep problems, and cognitive impairments. Many of these functions are regulated by μ-opioid receptor (MOR) system. Preclinical, in vivo, and post-mortem studies have however yielded inconclusive results regarding the rol...
Autores principales: | Nummenmaa, Lauri, Karjalainen, Tomi, Isojärvi, Janne, Kantonen, Tatu, Tuisku, Jouni, Kaasinen, Valtteri, Joutsa, Juho, Nuutila, Pirjo, Kalliokoski, Kari, Hirvonen, Jussi, Hietala, Jarmo, Rinne, Juha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608336/ https://www.ncbi.nlm.nih.gov/pubmed/32473595 http://dx.doi.org/10.1038/s41386-020-0725-9 |
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