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Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus
Prenatal infection during pregnancy increases the risk for developing neuropsychiatric disorders such as schizophrenia. This is linked to an inflammatory microglial phenotype in the offspring induced by maternal immune activation (MIA). Microglia are crucial for brain development and maintenance of...
Autores principales: | Xia, Yucen, Zhang, Zhiqing, Lin, Weipeng, Yan, Jinglan, Zhu, Chuan’an, Yin, Dongmin, He, Su, Su, Yang, Xu, Nenggui, Caldwell, Robert William, Yao, Lin, Chen, Yongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608378/ https://www.ncbi.nlm.nih.gov/pubmed/32599605 http://dx.doi.org/10.1038/s41386-020-0743-7 |
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