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Longitudinal follow-up of dome-shaped macula

BACKGROUND/OBJECTIVES: To determine if the presence of sub-retinal fluid (SRF) was associated with reduced vision in dome-shaped macula (DSM), and to assess its effect and response to treatment during follow-up. METHODS: Patients were identified retrospectively. Baseline and follow-up data were reco...

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Autores principales: Burke, Tomas R., Wu, Angela Ding, Shen, Yuening, Rajendram, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608413/
https://www.ncbi.nlm.nih.gov/pubmed/31969680
http://dx.doi.org/10.1038/s41433-020-0769-4
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author Burke, Tomas R.
Wu, Angela Ding
Shen, Yuening
Rajendram, Ranjan
author_facet Burke, Tomas R.
Wu, Angela Ding
Shen, Yuening
Rajendram, Ranjan
author_sort Burke, Tomas R.
collection PubMed
description BACKGROUND/OBJECTIVES: To determine if the presence of sub-retinal fluid (SRF) was associated with reduced vision in dome-shaped macula (DSM), and to assess its effect and response to treatment during follow-up. METHODS: Patients were identified retrospectively. Baseline and follow-up data were recorded. The diagnosis of DSM, and presence or absence of SRF and intra-retinal fluid (IRF) was confirmed using Spectral Domain-Optical Coherence Tomography (SD-OCT). Decisions to treat oedema were based on clinician preference. RESULTS: 193 eyes of 106 patients (71 female) were confirmed to have DSM. Overall mean duration of follow-up for this cohort was 3.5 years. Mean BRVA for all eyes at baseline was 0.38 (range: −0.20 to ‘light perception’). A significant difference was noted in mean baseline BRVA between those eyes with SRF compared with those without SRF at baseline (0.48 vs. 0.31, p < 0.001). Intra-retinal fluid moderately correlated with poorer baseline BRVA (r = 0.31, p < 0.003). No significant change in BRVA was noted during follow-up. No significant effect of treatment on BRVA was observed. CONCLUSIONS: The presence of SRF at baseline was associated with poorer vision. Vision appears to remain stable irrespective of the presence or absence of SRF at baseline. The treatments administered in this cohort did not affect final vision or SRF.
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spelling pubmed-76084132020-11-05 Longitudinal follow-up of dome-shaped macula Burke, Tomas R. Wu, Angela Ding Shen, Yuening Rajendram, Ranjan Eye (Lond) Article BACKGROUND/OBJECTIVES: To determine if the presence of sub-retinal fluid (SRF) was associated with reduced vision in dome-shaped macula (DSM), and to assess its effect and response to treatment during follow-up. METHODS: Patients were identified retrospectively. Baseline and follow-up data were recorded. The diagnosis of DSM, and presence or absence of SRF and intra-retinal fluid (IRF) was confirmed using Spectral Domain-Optical Coherence Tomography (SD-OCT). Decisions to treat oedema were based on clinician preference. RESULTS: 193 eyes of 106 patients (71 female) were confirmed to have DSM. Overall mean duration of follow-up for this cohort was 3.5 years. Mean BRVA for all eyes at baseline was 0.38 (range: −0.20 to ‘light perception’). A significant difference was noted in mean baseline BRVA between those eyes with SRF compared with those without SRF at baseline (0.48 vs. 0.31, p < 0.001). Intra-retinal fluid moderately correlated with poorer baseline BRVA (r = 0.31, p < 0.003). No significant change in BRVA was noted during follow-up. No significant effect of treatment on BRVA was observed. CONCLUSIONS: The presence of SRF at baseline was associated with poorer vision. Vision appears to remain stable irrespective of the presence or absence of SRF at baseline. The treatments administered in this cohort did not affect final vision or SRF. Nature Publishing Group UK 2020-01-22 2020-10 /pmc/articles/PMC7608413/ /pubmed/31969680 http://dx.doi.org/10.1038/s41433-020-0769-4 Text en © The Author(s), under exclusive licence to The Royal College of Ophthalmologists 2020
spellingShingle Article
Burke, Tomas R.
Wu, Angela Ding
Shen, Yuening
Rajendram, Ranjan
Longitudinal follow-up of dome-shaped macula
title Longitudinal follow-up of dome-shaped macula
title_full Longitudinal follow-up of dome-shaped macula
title_fullStr Longitudinal follow-up of dome-shaped macula
title_full_unstemmed Longitudinal follow-up of dome-shaped macula
title_short Longitudinal follow-up of dome-shaped macula
title_sort longitudinal follow-up of dome-shaped macula
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608413/
https://www.ncbi.nlm.nih.gov/pubmed/31969680
http://dx.doi.org/10.1038/s41433-020-0769-4
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