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The metabolic regulator Lamtor5 suppresses inflammatory signaling via regulating mTOR-mediated TLR4 degradation

Comprehensive immune responses are essential for eliminating pathogens but must be tightly controlled to avoid sustained immune activation and potential tissue damage. The engagement of TLR4, a canonical pattern recognition receptor, has been proposed to trigger inflammatory responses with different...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Zhuang, Ningtong, Liu, Xiaoyi, He, Long, He, Yan, Mahinthichaichan, Paween, Zhang, Hang, Kang, Yanhua, Lu, Yin, Wu, Qinan, Xu, Dakang, Shi, Liyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608472/
https://www.ncbi.nlm.nih.gov/pubmed/31467416
http://dx.doi.org/10.1038/s41423-019-0281-6