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Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway

Oxidative stress caused by chronic intermittent hypoxia (CIH) is the hallmark of obstructive sleep apnea (OSA). Among the first line of defense against oxidative stress is the dismutation of superoxide radicals, which in the mitochondria is carried out by manganese superoxide dismutase (SOD2). In th...

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Detalles Bibliográficos
Autores principales:	Song, Jie-qiong, Jiang, Li-yan, Fu, Cui-ping, Wu, Xu, Liu, Zi-long, Xie, Liang, Wu, Xiao-dan, Hao, Sheng-yu, Li, Shan-qun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608479/ https://www.ncbi.nlm.nih.gov/pubmed/32066884 http://dx.doi.org/10.1038/s41401-019-0349-y

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