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Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates
The heterotrimeric NatC complex, comprising the catalytic Naa30 and the two auxiliary subunits Naa35 and Naa38, co-translationally acetylates the N-termini of numerous eukaryotic target proteins. Despite its unique subunit composition, its essential role for many aspects of cellular function and its...
Autores principales: | Grunwald, Stephan, Hopf, Linus V. M., Bock-Bierbaum, Tobias, Lally, Ciara C. M., Spahn, Christian M. T., Daumke, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608589/ https://www.ncbi.nlm.nih.gov/pubmed/33139728 http://dx.doi.org/10.1038/s41467-020-19321-8 |
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