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Successful Deferasirox Rechallenge and Treating Through Reaction in a Patient with Challenge-Proven Mild Immediate Reaction: A Case Report

This is the first report of successful deferasirox administration, using graded challenge and treating through, in a patient with mild immediate hypersensitivity reaction. Beginning with drug graded challenges could indicate the eliciting dose and reaction severity which are important for the manage...

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Detalles Bibliográficos
Autores principales: Sompornrattanaphan, Mongkhon, Krikeerati, Thanachit, Wongsa, Chamard, Thongngarm, Torpong, Yampayon, Kittika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608632/
https://www.ncbi.nlm.nih.gov/pubmed/33154654
http://dx.doi.org/10.2147/JAA.S271742
Descripción
Sumario:This is the first report of successful deferasirox administration, using graded challenge and treating through, in a patient with mild immediate hypersensitivity reaction. Beginning with drug graded challenges could indicate the eliciting dose and reaction severity which are important for the management plan in the next step. This approach could be a safe shortcut in a stable patient with a mild reaction and a long avoidance period.