Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures

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We have designed a fully automated optical microscope running at high-speed and achieving a very high spatial resolution. In order to overcome the resolution limit of optical microscopes, it exploits the localized surface plasmon resonance phenomenon. The customized setup using a polarization analyz...

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Autores principales: Alexandrov, Andrey, Asada, Takashi, De Lellis, Giovanni, Di Crescenzo, Antonia, Gentile, Valerio, Naka, Tatsuhiro, Tioukov, Valeri, Umemoto, Atsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608637/
https://www.ncbi.nlm.nih.gov/pubmed/33139810
http://dx.doi.org/10.1038/s41598-020-75883-z
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author Alexandrov, Andrey
Asada, Takashi
De Lellis, Giovanni
Di Crescenzo, Antonia
Gentile, Valerio
Naka, Tatsuhiro
Tioukov, Valeri
Umemoto, Atsuhiro
author_facet Alexandrov, Andrey
Asada, Takashi
De Lellis, Giovanni
Di Crescenzo, Antonia
Gentile, Valerio
Naka, Tatsuhiro
Tioukov, Valeri
Umemoto, Atsuhiro
author_sort Alexandrov, Andrey
collection PubMed
description We have designed a fully automated optical microscope running at high-speed and achieving a very high spatial resolution. In order to overcome the resolution limit of optical microscopes, it exploits the localized surface plasmon resonance phenomenon. The customized setup using a polarization analyzer, based on liquid crystals, produces no vibrations and it is capable of probing isolated nanoparticles. We tested its performance with an automated readout using a fine-grained nuclear emulsion sample exposed to 60 keV carbon ion beam and, for the first time, successfully reconstructed the directional information from ultra-short tracks produced by such low-energetic ions using a solid-state tracking detector.
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spelling pubmed-76086372020-11-05 Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures Alexandrov, Andrey Asada, Takashi De Lellis, Giovanni Di Crescenzo, Antonia Gentile, Valerio Naka, Tatsuhiro Tioukov, Valeri Umemoto, Atsuhiro Sci Rep Article We have designed a fully automated optical microscope running at high-speed and achieving a very high spatial resolution. In order to overcome the resolution limit of optical microscopes, it exploits the localized surface plasmon resonance phenomenon. The customized setup using a polarization analyzer, based on liquid crystals, produces no vibrations and it is capable of probing isolated nanoparticles. We tested its performance with an automated readout using a fine-grained nuclear emulsion sample exposed to 60 keV carbon ion beam and, for the first time, successfully reconstructed the directional information from ultra-short tracks produced by such low-energetic ions using a solid-state tracking detector. Nature Publishing Group UK 2020-11-02 /pmc/articles/PMC7608637/ /pubmed/33139810 http://dx.doi.org/10.1038/s41598-020-75883-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Alexandrov, Andrey
Asada, Takashi
De Lellis, Giovanni
Di Crescenzo, Antonia
Gentile, Valerio
Naka, Tatsuhiro
Tioukov, Valeri
Umemoto, Atsuhiro
Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title_full Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title_fullStr Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title_full_unstemmed Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title_short Super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
title_sort super-resolution high-speed optical microscopy for fully automated readout of metallic nanoparticles and nanostructures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608637/
https://www.ncbi.nlm.nih.gov/pubmed/33139810
http://dx.doi.org/10.1038/s41598-020-75883-z
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