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Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction

Biomolecules form dynamic ensembles of many inter-converting conformations which are key for understanding how they fold and function. However, determining ensembles is challenging because the information required to specify atomic structures for thousands of conformations far exceeds that of experi...

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Detalles Bibliográficos
Autores principales: Shi, Honglue, Rangadurai, Atul, Abou Assi, Hala, Roy, Rohit, Case, David A., Herschlag, Daniel, Yesselman, Joseph D., Al-Hashimi, Hashim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608651/
https://www.ncbi.nlm.nih.gov/pubmed/33139729
http://dx.doi.org/10.1038/s41467-020-19371-y