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LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer

Cyclin D1 is one of the most important oncoproteins that drives cancer cell proliferation and associates with tamoxifen resistance in breast cancer. Here, we identify a lncRNA, DILA1, which interacts with Cyclin D1 and is overexpressed in tamoxifen-resistant breast cancer cells. Mechanistically, DIL...

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Detalles Bibliográficos
Autores principales: Shi, Qianfeng, Li, Yudong, Li, Shunying, Jin, Liang, Lai, Hongna, Wu, Yanqing, Cai, Zijie, Zhu, Mengdi, Li, Qian, Li, Ying, Wang, Jingru, Liu, Yujie, Wu, Zongqi, Song, Erwei, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608661/
https://www.ncbi.nlm.nih.gov/pubmed/33139730
http://dx.doi.org/10.1038/s41467-020-19349-w