The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization

Macrophages polarize into functionally distinct subtypes while responding to microenvironmental cues. The identity of proximal transcription factors (TFs) downstream from the polarization signals are known, but their activity is typically transient, failing to explain the long-term, stable epigenomi...

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Detalles Bibliográficos
Autores principales: Daniel, Bence, Czimmerer, Zsolt, Halasz, Laszlo, Boto, Pal, Kolostyak, Zsuzsanna, Poliska, Szilard, Berger, Wilhelm K., Tzerpos, Petros, Nagy, Gergely, Horvath, Attila, Hajas, György, Cseh, Timea, Nagy, Aniko, Sauer, Sascha, Francois-Deleuze, Jean, Szatmari, Istvan, Bacsi, Attila, Nagy, Laszlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608752/
https://www.ncbi.nlm.nih.gov/pubmed/33060136
http://dx.doi.org/10.1101/gad.343038.120

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