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The inositol pyrophosphate 5-InsP(7) drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α

Sodium/potassium-transporting adenosine triphosphatase (Na(+)/K(+)-ATPase) is one of the most abundant cell membrane proteins and is essential for eukaryotes. Endogenous negative regulators have long been postulated to play an important role in regulating the activity and stability of Na(+)/K(+)-ATP...

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Detalles Bibliográficos
Autores principales:	Chin, Alfred C., Gao, Zhe, Riley, Andrew M., Furkert, David, Wittwer, Christopher, Dutta, Amit, Rojas, Tomas, Semenza, Evan R., Felder, Robin A., Pluznick, Jennifer L., Jessen, Henning J., Fiedler, Dorothea, Potter, Barry V. L., Snyder, Solomon H., Fu, Chenglai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608788/ https://www.ncbi.nlm.nih.gov/pubmed/33115740 http://dx.doi.org/10.1126/sciadv.abb8542

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