Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructure

Humanized mouse models are increasingly studied to recapitulate human-like bone physiology. While human and mouse bone architectures differ in multiple scales, the extent to which chimeric human-mouse bone physiologically interacts and structurally integrates remains unknown. Here, we identify that...

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Detalles Bibliográficos
Autores principales: Moreno-Jiménez, I., Cipitria, A., Sánchez-Herrero, A., van Tol, A. F., Roschger, A., Lahr, C. A., McGovern, J. A., Hutmacher, D. W., Fratzl, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608795/
https://www.ncbi.nlm.nih.gov/pubmed/33115741
http://dx.doi.org/10.1126/sciadv.abb9265

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