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ACSL3–PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression

Pancreatic ductal adenocarcinoma (PDAC) is characterized by marked fibrosis and low immunogenicity, features that are linked to treatment resistance and poor clinical outcomes. Therefore, understanding how PDAC regulates the desmoplastic and immune stromal components is of great clinical importance....

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Detalles Bibliográficos
Autores principales: Rossi Sebastiano, Matteo, Pozzato, Chiara, Saliakoura, Maria, Yang, Zhang, Peng, Ren-Wang, Galiè, Mirco, Oberson, Kevin, Simon, Hans-Uwe, Karamitopoulou, Evanthia, Konstantinidou, Georgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608806/
https://www.ncbi.nlm.nih.gov/pubmed/33127675
http://dx.doi.org/10.1126/sciadv.abb9200