Leukemia-on-a-chip: Dissecting the chemoresistance mechanisms in B cell acute lymphoblastic leukemia bone marrow niche

B cell acute lymphoblastic leukemia (B-ALL) blasts hijack the bone marrow (BM) microenvironment to form chemoprotective leukemic BM “niches,” facilitating chemoresistance and, ultimately, disease relapse. However, the ability to dissect these evolving, heterogeneous interactions among distinct B-ALL...

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Detalles Bibliográficos
Autores principales: Ma, Chao, Witkowski, Matthew T., Harris, Jacob, Dolgalev, Igor, Sreeram, Sheetal, Qian, Weiyi, Tong, Jie, Chen, Xin, Aifantis, Iannis, Chen, Weiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608809/
https://www.ncbi.nlm.nih.gov/pubmed/33127669
http://dx.doi.org/10.1126/sciadv.aba5536

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