Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules

Many important proteins undergo pH-dependent conformational changes resulting in “on-off” switches for protein function, which are essential for regulation of life processes and have wide application potential. Here, we report a pair of cellulosomal assembly modules, comprising a cohesin and a docke...

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Detalles Bibliográficos
Autores principales: Yao, Xingzhe, Chen, Chao, Wang, Yefei, Dong, Sheng, Liu, Ya-Jun, Li, Yifei, Cui, Zhenling, Gong, Weibin, Perrett, Sarah, Yao, Lishan, Lamed, Raphael, Bayer, Edward A., Cui, Qiu, Feng, Yingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608827/
https://www.ncbi.nlm.nih.gov/pubmed/33097546
http://dx.doi.org/10.1126/sciadv.abd7182

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