Sexual dimorphism in the meiotic requirement for PRDM9: A mammalian evolutionary safeguard

In many mammals, genomic sites for recombination are determined by the histone methyltransferase PRMD9. Some mouse strains lacking PRDM9 are infertile, but instances of fertility or semifertility in the absence of PRDM9 have been reported in mice, canines, and a human female. Such findings raise the...

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Detalles Bibliográficos
Autores principales: Powers, Natalie R., Dumont, Beth L., Emori, Chihiro, Lawal, Raman Akinyanju, Brunton, Catherine, Paigen, Kenneth, Handel, Mary Ann, Bolcun-Filas, Ewelina, Petkov, Petko M., Bhattacharyya, Tanmoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608834/
https://www.ncbi.nlm.nih.gov/pubmed/33097538
http://dx.doi.org/10.1126/sciadv.abb6606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608834/
https://www.ncbi.nlm.nih.gov/pubmed/33097538
http://dx.doi.org/10.1126/sciadv.abb6606

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