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Phase separation as a therapeutic target in tight junction-associated human diseases

Tight junctions (TJs) play an important role in the maintenance of epithelial and endothelial barriers. Zonula occludens (ZO) proteins are scaffolding molecules essential for the formation of TJ complexes, and abnormalities in ZO proteins have been implicated in various TJ-associated human diseases...

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Detalles Bibliográficos
Autores principales: Sun, Shuang, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608859/
https://www.ncbi.nlm.nih.gov/pubmed/32694756
http://dx.doi.org/10.1038/s41401-020-0470-y

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