Antibacterial activity of a DNA topoisomerase I inhibitor versus fluoroquinolones in Streptococcus pneumoniae

The DNA topoisomerase complement of Streptococcus pneumoniae is constituted by two type II enzymes (topoisomerase IV and gyrase), and a single type I enzyme (topoisomerase I). These enzymes maintain the DNA topology, which is essential for replication and transcription. While fluoroquinolones target...

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Detalles Bibliográficos
Autores principales: Valenzuela, Myriam V., Domenech, Mirian, Mateos-Martínez, Patricia, González-Camacho, Fernando, de la Campa, Adela G., García, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608930/
https://www.ncbi.nlm.nih.gov/pubmed/33141832
http://dx.doi.org/10.1371/journal.pone.0241780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608930/
https://www.ncbi.nlm.nih.gov/pubmed/33141832
http://dx.doi.org/10.1371/journal.pone.0241780

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