Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution

Cerebral cavernous malformation (CCM) is a rare neurovascular disease that is characterized by enlarged and irregular blood vessels that often lead to cerebral hemorrhage. Loss-of-function mutations to any of three genes results in CCM lesion formation; namely, KRIT1, CCM2, and PDCD10 (CCM3). Here,...

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Detalles Bibliográficos
Autores principales: Orsenigo, Fabrizio, Conze, Lei Liu, Jauhiainen, Suvi, Corada, Monica, Lazzaroni, Francesca, Malinverno, Matteo, Sundell, Veronica, Cunha, Sara Isabel, Brännström, Johan, Globisch, Maria Ascención, Maderna, Claudio, Lampugnani, Maria Grazia, Magnusson, Peetra Ulrica, Dejana, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609066/
https://www.ncbi.nlm.nih.gov/pubmed/33138917
http://dx.doi.org/10.7554/eLife.61413

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