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Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells
Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells. However, although therapeutically effective, retinoids have only modest benefits and suffer from poor pharmacokinetic properties. In vivo, re...
Autores principales: | Bilip, Maja, Shah, Shreya, Mathiyalakan, Mayuran, Tagalakis, Aristides D., Hart, Stephen L., Maeshima, Ruhina, Eaton, Simon, Orford, Michael, Irving, Elsa, Di Florio, Alessia, Simons, Claire, Stoker, Andrew W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609071/ https://www.ncbi.nlm.nih.gov/pubmed/31903789 http://dx.doi.org/10.1080/1061186X.2019.1710157 |
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