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Deletion Timing of Cic Alleles during Hematopoiesis Determines the Degree of Peripheral CD4(+) T Cell Activation and Proliferation
Capicua (CIC) is a transcriptional repressor that regulates several developmental processes. CIC deficiency results in lymphoproliferative autoimmunity accompanied by expansion of CD44(hi)CD62L(lo) effector/memory and follicular Th cell populations. Deletion of Cic alleles in hematopoietic stem cell...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Korean Association of Immunologists
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609164/ https://www.ncbi.nlm.nih.gov/pubmed/33163251 http://dx.doi.org/10.4110/in.2020.20.e43 |