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Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer

INTRODUCTION: Although several medical, endoscopic, and surgical treatment options are available, the management of gastric antral vascular ectasia remains clinically challenging. We report a case of gastric antral vascular ectasia due to everolimus use in a patient with advanced renal cancer. CASE...

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Autores principales: Hata, Kenichi, Yasue, Keiji, Ishii, Gen, Kimura, Takahiro, Egawa, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609177/
https://www.ncbi.nlm.nih.gov/pubmed/33163931
http://dx.doi.org/10.1002/iju5.12221
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author Hata, Kenichi
Yasue, Keiji
Ishii, Gen
Kimura, Takahiro
Egawa, Shin
author_facet Hata, Kenichi
Yasue, Keiji
Ishii, Gen
Kimura, Takahiro
Egawa, Shin
author_sort Hata, Kenichi
collection PubMed
description INTRODUCTION: Although several medical, endoscopic, and surgical treatment options are available, the management of gastric antral vascular ectasia remains clinically challenging. We report a case of gastric antral vascular ectasia due to everolimus use in a patient with advanced renal cancer. CASE PRESENTATION: A 71‐year‐old man was diagnosed with right‐sided renal cancer and multiple lung metastases. In the period of everolimus as third‐line therapy, endoscopy of the upper gastrointestinal tract revealed everolimus‐induced gastric antral vascular ectasia. Endoscopic argon plasma coagulation and variceal ligation were repeated seven times within a month of everolimus cessation. Subsequently, an antrectomy was performed; his postoperative course was uneventful. CONCLUSION: Based on our experience, we believe that an antrectomy is important in the management of mammalian target of rapamycin inhibitor‐related gastric antral vascular ectasia.
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spelling pubmed-76091772020-11-06 Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer Hata, Kenichi Yasue, Keiji Ishii, Gen Kimura, Takahiro Egawa, Shin IJU Case Rep Case Reports INTRODUCTION: Although several medical, endoscopic, and surgical treatment options are available, the management of gastric antral vascular ectasia remains clinically challenging. We report a case of gastric antral vascular ectasia due to everolimus use in a patient with advanced renal cancer. CASE PRESENTATION: A 71‐year‐old man was diagnosed with right‐sided renal cancer and multiple lung metastases. In the period of everolimus as third‐line therapy, endoscopy of the upper gastrointestinal tract revealed everolimus‐induced gastric antral vascular ectasia. Endoscopic argon plasma coagulation and variceal ligation were repeated seven times within a month of everolimus cessation. Subsequently, an antrectomy was performed; his postoperative course was uneventful. CONCLUSION: Based on our experience, we believe that an antrectomy is important in the management of mammalian target of rapamycin inhibitor‐related gastric antral vascular ectasia. John Wiley and Sons Inc. 2020-09-21 /pmc/articles/PMC7609177/ /pubmed/33163931 http://dx.doi.org/10.1002/iju5.12221 Text en © 2020 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Urological Association This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Hata, Kenichi
Yasue, Keiji
Ishii, Gen
Kimura, Takahiro
Egawa, Shin
Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title_full Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title_fullStr Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title_full_unstemmed Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title_short Everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
title_sort everolimus‐induced gastric antral vascular ectasia in advanced renal cancer
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609177/
https://www.ncbi.nlm.nih.gov/pubmed/33163931
http://dx.doi.org/10.1002/iju5.12221
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