Cargando…
Drug development in targeting ion channels for brain edema
Cerebral edema is a pathological hallmark of various central nervous system (CNS) insults, including traumatic brain injury (TBI) and excitotoxic injury such as stroke. Due to the rigidity of the skull, edema-induced increase of intracranial fluid significantly complicates severe CNS injuries by rai...
Autores principales: | Luo, Zheng-wei, Ovcjak, Andrea, Wong, Raymond, Yang, Bao-xue, Feng, Zhong-ping, Sun, Hong-shuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609292/ https://www.ncbi.nlm.nih.gov/pubmed/32855530 http://dx.doi.org/10.1038/s41401-020-00503-5 |
Ejemplares similares
-
Hypothermia combined with neuroprotective adjuvants shortens the duration of hospitalization in infants with hypoxic ischemic encephalopathy: Meta-analysis
por: Ovcjak, Andrea, et al.
Publicado: (2023) -
NLRP3 Inflammasome: A Potential Target in Isoflurane Pretreatment Alleviates Stroke-Induced Retinal Injury in Diabetes
por: Lin, Hong-Bin, et al.
Publicado: (2021) -
Novel screening techniques for ion channel targeting drugs
por: Obergrussberger, Alison, et al.
Publicado: (2015) -
Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs
por: Michinaga, Shotaro, et al.
Publicado: (2015) -
Ion Channels as Drug Targets: The Next GPCRs
por: Kaczorowski, Gregory J., et al.
Publicado: (2008)