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A glycolipid adjuvant, 7DW8-5, provides a protective effect against colonic inflammation in mice by the recruitment of CD1d-restricted natural killer T cells

BACKGROUND/AIMS: The modulation of CD1d-restricted natural killer T (NKT) cells by glycolipids has been considered as a potential therapy against immunologic diseases, including inflammatory bowel disease. A recently identified a glycolipid analog, 7DW8-5, which is derived from α-galactosylceramide...

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Detalles Bibliográficos
Autores principales: Lee, Chansu, Hong, Sung Noh, Kim, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for the Study of Intestinal Diseases 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609397/
https://www.ncbi.nlm.nih.gov/pubmed/32248672
http://dx.doi.org/10.5217/ir.2019.00132