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Complement C1q Interacts With LRP1 Clusters II and IV Through a Site Close but Different From the Binding Site of Its C1r and C1s-Associated Proteases
LRP1 is a large endocytic modular receptor that plays a crucial role in the scavenging of apoptotic material through binding to pattern-recognition molecules. It is a membrane anchored receptor of the LDL receptor family with 4 extracellular clusters of ligand binding modules called cysteine rich co...
Autores principales: | Fouët, Guillaume, Gout, Evelyne, Wicker-Planquart, Catherine, Bally, Isabelle, De Nardis, Camilla, Dedieu, Stéphane, Chouquet, Anne, Gaboriaud, Christine, Thielens, Nicole M., Kleman, Jean-Philippe, Rossi, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609443/ https://www.ncbi.nlm.nih.gov/pubmed/33193398 http://dx.doi.org/10.3389/fimmu.2020.583754 |
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