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Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor

Glucocorticoid (GC) actions are mediated through two closely related ligand-dependent transcription factors, the GC receptor (GR) and the mineralocorticoid receptor (MR). Given the wide and effective use of GCs to combat skin inflammatory diseases, it is important to understand the relative contribu...

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Detalles Bibliográficos
Autores principales: Sevilla, Lisa M., Bigas, Judit, Chiner-Oms, Álvaro, Comas, Iñaki, Sentandreu, Vicente, Pérez, Paloma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609727/
https://www.ncbi.nlm.nih.gov/pubmed/33144612
http://dx.doi.org/10.1038/s41598-020-75853-5

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