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Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor
Glucocorticoid (GC) actions are mediated through two closely related ligand-dependent transcription factors, the GC receptor (GR) and the mineralocorticoid receptor (MR). Given the wide and effective use of GCs to combat skin inflammatory diseases, it is important to understand the relative contribu...
Autores principales: | Sevilla, Lisa M., Bigas, Judit, Chiner-Oms, Álvaro, Comas, Iñaki, Sentandreu, Vicente, Pérez, Paloma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609727/ https://www.ncbi.nlm.nih.gov/pubmed/33144612 http://dx.doi.org/10.1038/s41598-020-75853-5 |
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