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Examination of Fas-Induced Apoptosis of Murine Thymocytes in Thymic Tissue Slices Reveals That Fas Is Dispensable for Negative Selection
The death receptor Fas can induce cell death through the extrinsic pathway of apoptosis in a variety of cells, including developing thymocytes. Although Fas-induced cell death has been researched and modeled extensively, most of the studies have been done in vitro because of the lethality of Fas tri...
Autores principales: | Chu, Chang-Feng, Feng, Hsing-Kai, Sun, Kuang-Hui, Hsu, Chia-Lin, Dzhagalov, Ivan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609743/ https://www.ncbi.nlm.nih.gov/pubmed/33195241 http://dx.doi.org/10.3389/fcell.2020.586807 |
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