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Wake-Promoting and EEG Spectral Effects of Modafinil After Acute or Chronic Administration in the R6/2 Mouse Model of Huntington’s Disease
Huntington’s disease (HD) is characterised by progressive symptoms including cognitive deficits and sleep/wake disturbances reflected in an abnormal electroencephalography (EEG). Modafinil, a wake-promoting and cognitive-enhancing drug, has been considered as a treatment for HD. We used HD (R6/2) mi...
Autores principales: | Vas, Szilvia, Casey, Jackie M., Schneider, Will T., Kalmar, Lajos, Morton, A. Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609772/ https://www.ncbi.nlm.nih.gov/pubmed/32297185 http://dx.doi.org/10.1007/s13311-020-00849-y |
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