Quaternary Ammonium Compound Disinfectants Reduce Lupus-Associated Splenomegaly by Targeting Neutrophil Migration and T-Cell Fate

Hypersensitivity reactions and immune dysregulation have been reported with the use of quaternary ammonium compound disinfectants (QACs). We hypothesized that QAC exposure would exacerbate autoimmunity associated with systemic lupus erythematosus (lupus). Surprisingly, however, we found that compare...

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Detalles Bibliográficos
Autores principales: Abdelhamid, Leila, Cabana-Puig, Xavier, Mu, Qinghui, Moarefian, Maryam, Swartwout, Brianna, Eden, Kristin, Das, Prerna, Seguin, Ryan P., Xu, Libin, Lowen, Sarah, Lavani, Mital, Hrubec, Terry C., Jones, Caroline N., Luo, Xin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609861/
https://www.ncbi.nlm.nih.gov/pubmed/33193366
http://dx.doi.org/10.3389/fimmu.2020.575179

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