Gm614 Protects Germinal Center B Cells From Death by Suppressing Caspase-1 Transcription in Lupus-Prone Mice

Only a few signaling pathways have been reported in germinal center (GC) B-cell proliferation and death. In this study, we showed that a novel uncharacterized Gm614 protein is highly expressed in GC B cells from lupus-prone mice. Critically, ablation of this GC B-cell-specific Gm614 promoted GC B-ce...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Youdi, Xu, Ruonan, Zhai, Bing, Zhou, Shan, Wang, Xiaoqian, Wang, Renxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609865/
https://www.ncbi.nlm.nih.gov/pubmed/33193409
http://dx.doi.org/10.3389/fimmu.2020.585726

Ejemplares similares

Ejemplares similares