Functional Interactions of Tau Phosphorylation Sites That Mediate Toxicity and Deficient Learning in Drosophila melanogaster

Hyperphosphorylated Tau protein is the main component of the neurofibrillary tangles, characterizing degenerating neurons in Alzheimer’s disease and other Tauopathies. Expression of human Tau protein in Drosophila CNS results in increased toxicity, premature mortality and learning and memory deficit...

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Detalles Bibliográficos
Autores principales: Keramidis, Iason, Vourkou, Ergina, Papanikolopoulou, Katerina, Skoulakis, Efthimios M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609872/
https://www.ncbi.nlm.nih.gov/pubmed/33192295
http://dx.doi.org/10.3389/fnmol.2020.569520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609872/
https://www.ncbi.nlm.nih.gov/pubmed/33192295
http://dx.doi.org/10.3389/fnmol.2020.569520

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