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Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature

BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were fill...

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Autores principales: Sahoo, Pradyumna Kumar, Patnayak, Rashmi, Khan, Perwez Alam, Jena, Amitabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610023/
https://www.ncbi.nlm.nih.gov/pubmed/33137673
http://dx.doi.org/10.1016/j.ijscr.2020.10.058
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author Sahoo, Pradyumna Kumar
Patnayak, Rashmi
Khan, Perwez Alam
Jena, Amitabh
author_facet Sahoo, Pradyumna Kumar
Patnayak, Rashmi
Khan, Perwez Alam
Jena, Amitabh
author_sort Sahoo, Pradyumna Kumar
collection PubMed
description BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis. CASE REPORT: A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II – level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well. CONCLUSION: Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management.
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spelling pubmed-76100232020-11-06 Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature Sahoo, Pradyumna Kumar Patnayak, Rashmi Khan, Perwez Alam Jena, Amitabh Int J Surg Case Rep Case Report BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis. CASE REPORT: A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II – level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well. CONCLUSION: Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management. Elsevier 2020-10-22 /pmc/articles/PMC7610023/ /pubmed/33137673 http://dx.doi.org/10.1016/j.ijscr.2020.10.058 Text en © 2020 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Sahoo, Pradyumna Kumar
Patnayak, Rashmi
Khan, Perwez Alam
Jena, Amitabh
Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title_full Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title_fullStr Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title_full_unstemmed Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title_short Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
title_sort warthin-like variant of papillary thyroid carcinoma—case report of an uncommon tumour with review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610023/
https://www.ncbi.nlm.nih.gov/pubmed/33137673
http://dx.doi.org/10.1016/j.ijscr.2020.10.058
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