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Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature
BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were fill...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610023/ https://www.ncbi.nlm.nih.gov/pubmed/33137673 http://dx.doi.org/10.1016/j.ijscr.2020.10.058 |
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author | Sahoo, Pradyumna Kumar Patnayak, Rashmi Khan, Perwez Alam Jena, Amitabh |
author_facet | Sahoo, Pradyumna Kumar Patnayak, Rashmi Khan, Perwez Alam Jena, Amitabh |
author_sort | Sahoo, Pradyumna Kumar |
collection | PubMed |
description | BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis. CASE REPORT: A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II – level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well. CONCLUSION: Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management. |
format | Online Article Text |
id | pubmed-7610023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-76100232020-11-06 Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature Sahoo, Pradyumna Kumar Patnayak, Rashmi Khan, Perwez Alam Jena, Amitabh Int J Surg Case Rep Case Report BACKGROUND: Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis. CASE REPORT: A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II – level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well. CONCLUSION: Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management. Elsevier 2020-10-22 /pmc/articles/PMC7610023/ /pubmed/33137673 http://dx.doi.org/10.1016/j.ijscr.2020.10.058 Text en © 2020 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Sahoo, Pradyumna Kumar Patnayak, Rashmi Khan, Perwez Alam Jena, Amitabh Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title | Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title_full | Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title_fullStr | Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title_full_unstemmed | Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title_short | Warthin-like variant of Papillary thyroid carcinoma—Case report of an uncommon tumour with review of literature |
title_sort | warthin-like variant of papillary thyroid carcinoma—case report of an uncommon tumour with review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610023/ https://www.ncbi.nlm.nih.gov/pubmed/33137673 http://dx.doi.org/10.1016/j.ijscr.2020.10.058 |
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