Cargando…

CD‐1(db/db) mice: A novel type 2 diabetic mouse model with progressive kidney fibrosis

AIMS/INTRODUCTION: To establish novel therapies to combat diabetic kidney disease, a human disease‐relevant animal model is essential. However, a type 2 diabetic mouse model presenting progressive kidney fibrosis has not yet been established. Kidneys of streptozotocin‐induced diabetic CD‐1 mice show...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mizunuma, Yuiko, Kanasaki, Keizo, Nitta, Kyoko, Nakamura, Yuka, Ishigaki, Yasuhito, Takagaki, Yuta, Kitada, Munehiro, Li, Shaolan, Liu, Haijie, Li, Jinpeng, Usui, Isao, Aso, Yoshimasa, Koya, Daisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610117/ https://www.ncbi.nlm.nih.gov/pubmed/32472621 http://dx.doi.org/10.1111/jdi.13311

Ejemplares similares

Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high‐fat diet
por: Takagi, Susumu, et al.
Publicado: (2018)

Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys
por: Srivastava, Swayam Prakash, et al.
Publicado: (2021)

N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes
por: Kanasaki, Keizo, et al.
Publicado: (2014)

Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice
por: Takagaki, Yuta, et al.
Publicado: (2019)

N-acetyl-seryl-aspartyl-lysyl-proline Inhibits Diabetes-Associated Kidney Fibrosis and Endothelial-Mesenchymal Transition
por: Nagai, Takako, et al.
Publicado: (2014)

Deficiency in Dipeptidyl Peptidase-4 Promotes Chemoresistance Through the CXCL12/CXCR4/mTOR/TGFβ Signaling Pathway in Breast Cancer Cells
por: Li, Shaolan, et al.
Publicado: (2020)

Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis
por: Srivastava, Swayam Prakash, et al.
Publicado: (2016)

FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway
por: Li, Jinpeng, et al.
Publicado: (2017)

βklotho is essential for the anti‐endothelial mesenchymal transition effects of N‐acetyl‐seryl‐aspartyl‐lysyl‐proline
por: Gao, Rongfen, et al.
Publicado: (2019)

The PKM2 activator TEPP‐46 suppresses kidney fibrosis via inhibition of the EMT program and aberrant glycolysis associated with suppression of HIF‐1α accumulation
por: Liu, Haijie, et al.
Publicado: (2020)

Severe electrolytes disorders with the interstitial kidney alterations in the patient with the history of total thyroidectomy and parathyroidectomy: possible role of vitamin D deficiency
por: Kawakita, Emi, et al.
Publicado: (2018)

Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen
por: Nitta, Kyoko, et al.
Publicado: (2016)

Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors
por: Kanasaki, Megumi, et al.
Publicado: (2011)

Adenosine/adenosine type 1 receptor signaling pathway did not play dominant roles on the influence of sodium–glucose cotransporter 2 inhibitor in the kidney of bovine serum albumin‐overloaded streptozotocin‐induced diabetic mice
por: Shimada, Keiji, et al.
Publicado: (2022)

Diabetic angiopathy and angiogenic defects
por: Xu, Ling, et al.
Publicado: (2012)

Effect of switching to teneligliptin from other dipeptidyl peptidase‐4 inhibitors on glucose control and renoprotection in type 2 diabetes patients with diabetic kidney disease
por: Kitada, Munehiro, et al.
Publicado: (2018)

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy
por: Kitada, Munehiro, et al.
Publicado: (2012)

SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis
por: Srivastava, Swayam Prakash, et al.
Publicado: (2018)

Dietary Restriction Ameliorates Diabetic Nephropathy through Anti-Inflammatory Effects and Regulation of the Autophagy via Restoration of Sirt1 in Diabetic Wistar Fatty (fa/fa) Rats: A Model of Type 2 Diabetes
por: Kitada, Munehiro, et al.
Publicado: (2011)

Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats
por: Ogura, Yoshio, et al.
Publicado: (2018)

Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice
por: Kanasaki, Megumi, et al.
Publicado: (2017)

Autophagy as a Therapeutic Target in Diabetic Nephropathy
por: Tanaka, Yuki, et al.
Publicado: (2012)

A low-protein diet exerts a beneficial effect on diabetic status and prevents diabetic nephropathy in Wistar fatty rats, an animal model of type 2 diabetes and obesity
por: Kitada, Munehiro, et al.
Publicado: (2018)

Inhibition of Dipeptidyl Peptidase-4 Activates Autophagy to Promote Survival of Breast Cancer Cells via the mTOR/HIF-1α Pathway
por: Kawakita, Emi, et al.
Publicado: (2023)

Cosmos DB for MongoDB developers: migrating to Azure Cosmos DB and using the MongoDB API
por: Sharma, Manish
Publicado: (2018)

Classical molecule in diabetic kidney hypertrophy is linked to defects in self‐eating through fine‐tuning
por: Takagaki, Yuta, et al.
Publicado: (2021)

Dapagliflozin Restores Impaired Autophagy and Suppresses Inflammation in High Glucose-Treated HK-2 Cells
por: Xu, Jing, et al.
Publicado: (2021)

The Effect of Piceatannol from Passion Fruit (Passiflora edulis) Seeds on Metabolic Health in Humans
por: Kitada, Munehiro, et al.
Publicado: (2017)

Anti-diabetic activities of catalpol in db/db mice
por: Bao, Qinwen, et al.
Publicado: (2016)

The role of chicken eggs in modulating sarcopenic obesity and gut microbiota in db/db mice
por: Okamura, Takuro, et al.
Publicado: (2023)

Antidiabetic and Antiobesity Effects of Artemether in db/db Mice
por: Guo, Yu, et al.
Publicado: (2018)

Restoration of the Hypothalamic-pituitary-adrenal Response to Hypoglycemia in Type 2 Diabetes by Avoiding Chronic Hypoglycemia
por: Tsuda, Shin-ichi, et al.
Publicado: (2016)

Mibefradil reduces blood glucose concentration in db/db mice
por: Lu, Yujie, et al.
Publicado: (2014)

Neuregulin 1 Improves Glucose Tolerance in db/db Mice
por: Ennequin, Gaël, et al.
Publicado: (2015)

Astragaloside IV ameliorates renal injury in db/db mice
por: Sun, Huili, et al.
Publicado: (2016)

Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
por: Qiao, Panshuang, et al.
Publicado: (2022)

Debuncher DB1 (DB2 and DB3): 1 A06 - 000 - 1
por: Boltezar, E
Publicado: (1970)

Debuncher DB1 (DB2 and DB3): I A06-000-1
por: Boltezar, E
Publicado: (1970)

Anagliptin ameliorates albuminuria and urinary liver-type fatty acid-binding protein excretion in patients with type 2 diabetes with nephropathy in a glucose-lowering-independent manner
por: Kitada, Munehiro, et al.
Publicado: (2017)

Artemether Regulates Metaflammation to Improve Glycolipid Metabolism in db/db Mice
por: Fu, Wei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sselmscprhejoqqpkm4labq0hs