Cargando…
CircSERPINE2 weakens IL-1β-caused apoptosis and extracellular matrix degradation of chondrocytes by regulating miR-495/TGFBR2 axis
The dysregulated circular RNAs (circRNAs) are relevant to the development of osteoarthritis (OA). The circRNA serpin family E member 2 (circSERPINE2) is dysregulated in OA, while the role and mechanism of circSERPINE2 in OA are largely unknown. The aim of our research is to explore how and whether c...
Autores principales: | Zhang, Qingpu, Qiao, Xiaomiao, Xia, Wenwei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610148/ https://www.ncbi.nlm.nih.gov/pubmed/33094798 http://dx.doi.org/10.1042/BSR20201601 |
Ejemplares similares
-
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis
por: Chen, Fenglei, et al.
Publicado: (2023) -
CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene
por: Shen, Shuying, et al.
Publicado: (2019) -
Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway
por: Zhao, Yu, et al.
Publicado: (2020) -
Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis
por: He, Qi, et al.
Publicado: (2021) -
Matrine regulates H(2)O(2)-induced oxidative stress through long non-coding RNA HOTAIR/miR-106b-5p axis via AKT and STAT3 pathways
por: Xu, Guanxue, et al.
Publicado: (2020)