The design and synthesis of dextran-doxorubicin prodrug-based pH-sensitive drug delivery system for improving chemotherapy efficacy

Tumor cells show acidic conditions compared with normal cells, which further inspires scientist to build nanocarrier responsive to tumor microenvironment (TME) for enhancing tumor therapeutic efficacy. Here, we report a pH-sensitive and biocompatible polyprodrug based on dextran-doxorubicin (DOX) pr...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoli, Zhang, Tian, Ma, Xianbin, Wang, Yajun, Lu, Yi, Jia, Die, Huang, Xiaohua, Chen, Jiucun, Xu, Zhigang, Wen, Feiqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610203/
https://www.ncbi.nlm.nih.gov/pubmed/33193863
http://dx.doi.org/10.1016/j.ajps.2019.10.001

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