Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement

A magnetic molecularly imprinted silica solid was obtained by sol-gel polymerization for the separation of domoic acid. The solid showed rapid adsorption kinetics with an adsorption equilibrium time of 5 min. The solid showed affinity to domoic acid under the interference of tryptophan and could be...

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Detalles Bibliográficos
Autores principales: Lin, Zhengzhong, Chen, Shengyang, Li, Lei, Peng, Aihong, Huang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610248/
https://www.ncbi.nlm.nih.gov/pubmed/33163648
http://dx.doi.org/10.1016/j.heliyon.2020.e05287
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author Lin, Zhengzhong
Chen, Shengyang
Li, Lei
Peng, Aihong
Huang, Zhiyong
author_facet Lin, Zhengzhong
Chen, Shengyang
Li, Lei
Peng, Aihong
Huang, Zhiyong
author_sort Lin, Zhengzhong
collection PubMed
description A magnetic molecularly imprinted silica solid was obtained by sol-gel polymerization for the separation of domoic acid. The solid showed rapid adsorption kinetics with an adsorption equilibrium time of 5 min. The solid showed affinity to domoic acid under the interference of tryptophan and could be repeatedly used for 5 times at least. The solid was used as a solid-phase-extraction sorbent for the extraction of domoic acid from clam samples before measurement with liquid chromatography. The detection limit of 0.20 mg kg(−1) was lower than the allowable limits in several countries or areas. The recoveries in the spiked samples were 88% approximately.
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spelling pubmed-76102482020-11-06 Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement Lin, Zhengzhong Chen, Shengyang Li, Lei Peng, Aihong Huang, Zhiyong Heliyon Research Article A magnetic molecularly imprinted silica solid was obtained by sol-gel polymerization for the separation of domoic acid. The solid showed rapid adsorption kinetics with an adsorption equilibrium time of 5 min. The solid showed affinity to domoic acid under the interference of tryptophan and could be repeatedly used for 5 times at least. The solid was used as a solid-phase-extraction sorbent for the extraction of domoic acid from clam samples before measurement with liquid chromatography. The detection limit of 0.20 mg kg(−1) was lower than the allowable limits in several countries or areas. The recoveries in the spiked samples were 88% approximately. Elsevier 2020-10-26 /pmc/articles/PMC7610248/ /pubmed/33163648 http://dx.doi.org/10.1016/j.heliyon.2020.e05287 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Lin, Zhengzhong
Chen, Shengyang
Li, Lei
Peng, Aihong
Huang, Zhiyong
Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title_full Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title_fullStr Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title_full_unstemmed Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title_short Rapid extraction of domoic acid by a magnetic molecularly imprinted silica before HPLC measurement
title_sort rapid extraction of domoic acid by a magnetic molecularly imprinted silica before hplc measurement
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610248/
https://www.ncbi.nlm.nih.gov/pubmed/33163648
http://dx.doi.org/10.1016/j.heliyon.2020.e05287
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