Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma

While the transition metal copper (Cu) is an essential nutrient that is conventionally viewed as a static cofactor within enzyme active sites, a nontraditional role for Cu as a modulator of kinase signaling is emerging. We discovered that Cu is required for the activity of the autophagic kinases ULK...

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Detalles Bibliográficos
Autores principales: Tsang, Tiffany, Posimo, Jessica M., Gudiel, Andrea A., Cicchini, Michelle, Feldser, David M., Brady, Donita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610258/
https://www.ncbi.nlm.nih.gov/pubmed/32203415
http://dx.doi.org/10.1038/s41556-020-0481-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610258/
https://www.ncbi.nlm.nih.gov/pubmed/32203415
http://dx.doi.org/10.1038/s41556-020-0481-4

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