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Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma
While the transition metal copper (Cu) is an essential nutrient that is conventionally viewed as a static cofactor within enzyme active sites, a nontraditional role for Cu as a modulator of kinase signaling is emerging. We discovered that Cu is required for the activity of the autophagic kinases ULK...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610258/ https://www.ncbi.nlm.nih.gov/pubmed/32203415 http://dx.doi.org/10.1038/s41556-020-0481-4 |