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Dynamics in protein translation sustaining T cell preparedness

In response to pathogenic threats, naïve T cells rapidly transition from a quiescent to activated state, yet the underlying mechanisms are incompletely understood. Using a pulsed SILAC approach, we investigated the dynamics of mRNA translation kinetics and protein turnover in human naïve and activat...

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Detalles Bibliográficos
Autores principales:	Wolf, Tobias, Jin, Wenjie, Zoppi, Giada, Vogel, Ian A., Akhmedov, Murodzhon, Bleck, Christopher K.E., Beltraminelli, Tim, Rieckmann, Jan C., Ramirez, Neftali J., Benevento, Marco, Notarbartolo, Samuele, Bumann, Dirk, Meissner, Felix, Grimbacher, Bodo, Mann, Matthias, Lanzavecchia, Antonio, Sallusto, Federica, Kwee, Ivo, Geiger, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610365/ https://www.ncbi.nlm.nih.gov/pubmed/32632289 http://dx.doi.org/10.1038/s41590-020-0714-5

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