A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome

The mechanistic target of rapamycin complex 1 (mTORC1) is a key metabolic hub that controls the cellular response to environmental cues by exerting its kinase activity on multiple substrates(1–3). However, whether mTORC1 responds to diverse stimuli by differentially phosphorylating specific substrat...

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Detalles Bibliográficos
Autores principales: Napolitano, Gennaro, Di Malta, Chiara, Esposito, Alessandra, de Araujo, Mariana E.G., Pece, Salvatore, Bertalot, Giovanni, Matarese, Maria, Benedetti, Valerio, Zampelli, Angela, Stasyk, Taras, Siciliano, Diletta, Venuta, Alessandro, Cesana, Marcella, Vilardo, Claudia, Nusco, Edoardo, Monfregola, Jlenia, Calcagni, Alessia, Di Fiore, Pier Paolo, Huber, Lukas A., Ballabio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610377/
https://www.ncbi.nlm.nih.gov/pubmed/32612235
http://dx.doi.org/10.1038/s41586-020-2444-0

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