Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy

Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodeling during stress. Here we show that Mitochondrial Pyruvate Carrier (MPC) abundance mediates pathological cardiac hypertrophy. MPC abundance was reduced in failing hypertrophic human hearts,...

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Detalles Bibliográficos
Autores principales: Fernandez-Caggiano, Mariana, Kamynina, Alisa, Francois, Asvi A., Prysyazhna, Oleksandra, Eykyn, Thomas R., Krasemann, Susanne, Crespo-Leiro, Maria G., Vieites, Maria Garcia, Bianchi, Katiuscia, Morales, Valle, Domenech, Nieves, Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610404/
https://www.ncbi.nlm.nih.gov/pubmed/33106688
http://dx.doi.org/10.1038/s42255-020-00276-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610404/
https://www.ncbi.nlm.nih.gov/pubmed/33106688
http://dx.doi.org/10.1038/s42255-020-00276-5

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