MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki Syndrome

The genetic elements required to tune gene expression are partitioned in active and repressive nuclear condensates. Chromatin compartments include transcriptional clusters whose dynamic establishment and functioning depends on multivalent interactions occurring among transcription factors, cofactors...

Descripción completa

Detalles Bibliográficos
Autores principales: Fasciani, Alessandra, D’Annunzio, Sarah, Poli, Vittoria, Fagnocchi, Luca, Beyes, Sven, Michelatti, Daniela, Corazza, Francesco, Antonelli, Laura, Gregoretti, Francesco, Oliva, Gennaro, Belli, Romina, Peroni, Daniele, Domenici, Enrico, Zambrano, Samuel, Intartaglia, Daniela, Settembre, Carmine, Conte, Ivan, Testi, Claudia, Vergyris, Panagiotis, Ruocco, Giancarlo, Zippo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610431/
https://www.ncbi.nlm.nih.gov/pubmed/33169020
http://dx.doi.org/10.1038/s41588-020-00724-8

Ejemplares similares

Ejemplares similares