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Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains

Many biochemical reactions require controlled recruitment of proteins to membranes. This is largely regulated by post-translational modifications. A frequent one is S-acylation, which consists of the addition of acyl chains and can be reversed by poorly understood acyl protein thioesterases (APTs)....

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Detalles Bibliográficos
Autores principales: Abrami, Laurence, Audagnotto, Martina, Ho, Sylvia, Marcaida, Maria Jose, Mesquita, Francisco S., Anwar, Muhammad U., Sandoz, Patrick A., Fonti, Giulia, Pojer, Florence, Peraro, Matteo Dal, van der Goot, F. Gisou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610442/
https://www.ncbi.nlm.nih.gov/pubmed/33707782
http://dx.doi.org/10.1038/s41589-021-00753-2