Cargando…

Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains

Many biochemical reactions require controlled recruitment of proteins to membranes. This is largely regulated by post-translational modifications. A frequent one is S-acylation, which consists of the addition of acyl chains and can be reversed by poorly understood acyl protein thioesterases (APTs)....

Descripción completa

Detalles Bibliográficos
Autores principales:	Abrami, Laurence, Audagnotto, Martina, Ho, Sylvia, Marcaida, Maria Jose, Mesquita, Francisco S., Anwar, Muhammad U., Sandoz, Patrick A., Fonti, Giulia, Pojer, Florence, Peraro, Matteo Dal, van der Goot, F. Gisou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610442/ https://www.ncbi.nlm.nih.gov/pubmed/33707782 http://dx.doi.org/10.1038/s41589-021-00753-2

Ejemplares similares

Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin
por: Dallavilla, Tiziano, et al.
Publicado: (2016)

Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation
por: Gu, Mengru, et al.
Publicado: (2023)

Dynamics of CLIMP-63 S-acylation control ER morphology
por: Sandoz, Patrick A., et al.
Publicado: (2023)

Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)
por: Segal-Salto, Michal, et al.
Publicado: (2016)

S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
por: Mesquita, Francisco S., et al.
Publicado: (2021)

Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications
por: Anwar, Muhammad U., et al.
Publicado: (2023)

Protein S-acyltransferases and acyl protein thioesterases, regulation executors of protein S-acylation in plants
por: Li, Jincheng, et al.
Publicado: (2022)

Construction of efficient and effective transformation vectors for palmitoyl-acyl carrier protein thioesterase gene silencing in oil palm
por: Bhore, Subhash Janardhan, et al.
Publicado: (2011)

Two distinct domains contribute to the substrate acyl chain length selectivity of plant acyl-ACP thioesterase
por: Jing, Fuyuan, et al.
Publicado: (2018)

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis
por: Abrami, Laurence, et al.
Publicado: (2006)

SwissPalm: Protein Palmitoylation database
por: Blanc, Mathieu, et al.
Publicado: (2015)

Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade
por: Abrami, Laurence, et al.
Publicado: (2017)

Development of an activity-based probe for acyl-protein thioesterases
por: Garland, Megan, et al.
Publicado: (2018)

Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells
por: Vujic, Igor, et al.
Publicado: (2016)

Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo
por: Solis, Gonzalo P., et al.
Publicado: (2022)

Characterization of the acyl-ACP thioesterases from Koelreuteria paniculata reveals a new type of FatB thioesterase
por: Martins-Noguerol, R., et al.
Publicado: (2020)

Determinants of substrate specificity in a catalytically diverse family of acyl-ACP thioesterases from plants
por: Kalinger, Rebecca S., et al.
Publicado: (2023)

Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity
por: Brown, Robert W. B., et al.
Publicado: (2022)

Palmitoylation: a protein S-acylation with implications for breast cancer
por: Anderson, Alison M, et al.
Publicado: (2016)

Conformational Changes of Acyl Carrier Protein Switch the Chain Length Preference of Acyl-ACP Thioesterase ChFatB2
por: Yang, Tianxiang, et al.
Publicado: (2023)

The thioesterase APT1 is a bidirectional-adjustment redox sensor
por: Ji, Tuo, et al.
Publicado: (2023)

Analysis of the brain palmitoyl-proteome using both acyl-biotin exchange and acyl-resin-assisted capture methods
por: Edmonds, Matthew J., et al.
Publicado: (2017)

Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5
por: Brigidi, G. Stefano, et al.
Publicado: (2015)

Acyl-Protein Thioesterase 2 Catalizes the Deacylation of Peripheral Membrane-Associated GAP-43
por: Tomatis, Vanesa M., et al.
Publicado: (2010)

2-Bromopalmitate Reduces Protein Deacylation by Inhibition of Acyl-Protein Thioesterase Enzymatic Activities
por: Pedro, Maria P., et al.
Publicado: (2013)

Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family
por: Brocker, Chad, et al.
Publicado: (2010)

T181. PROTEIN ACYL-THIOESTERASE ENZYME ACTIVITY IN THE POSTMORTEM DORSOLATERAL PREFRONTAL CORTEX IN SCHIZOPHRENIA
por: Hopper, Shaun, et al.
Publicado: (2020)

S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca(2+) signaling by Jurkat T cell receptors at the immune synapse
por: Carreras-Sureda, Amado, et al.
Publicado: (2021)

Acyl-CoA thioesterase activity of peroxisomal ABC protein ABCD1 is required for the transport of very long-chain acyl-CoA into peroxisomes
por: Kawaguchi, Kosuke, et al.
Publicado: (2021)

Plasmodium palmitoylation machinery engineered in E. coli for high‐throughput screening of palmitoyl acyl‐transferase inhibitors
por: Yadav, Preeti, et al.
Publicado: (2019)

Distinct Acyl Protein Transferases and Thioesterases Control Surface Expression of Calcium-activated Potassium Channels
por: Tian, Lijun, et al.
Publicado: (2012)

Toward production of jet fuel functionality in oilseeds: identification of FatB acyl-acyl carrier protein thioesterases and evaluation of combinatorial expression strategies in Camelina seeds
por: Kim, Hae Jin, et al.
Publicado: (2015)

Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity
por: Jing, Fuyuan, et al.
Publicado: (2011)

Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma
por: Xu, Chao-Liang, et al.
Publicado: (2020)

Low expression of acyl-CoA thioesterase 13 is associated with poor prognosis in ovarian serous cystadenocarcinoma
por: Lv, Xiaofeng, et al.
Publicado: (2023)

Author Correction: The thioesterase APT1 is a bidirectional-adjustment redox sensor
por: Ji, Tuo, et al.
Publicado: (2023)

Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach
por: Mayer, Kimberly M, et al.
Publicado: (2007)

Depalmitoylation by Palmitoyl-Protein Thioesterase 1 in Neuronal Health and Degeneration
por: Koster, Kevin P., et al.
Publicado: (2019)

Cloning of Acyl-ACP Thioesterase FatA from Arachis hypogaea L. and Its Expression in Escherichia coli
por: Chen, Gao, et al.
Publicado: (2012)

The role of the acyl-CoA thioesterase “YciA” in the production of (R)-3-hydroxybutyrate by recombinant Escherichia coli
por: Guevara-Martínez, Mónica, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_39nksksbu7l1h6mq4483i8ekum